Purdue's NCAA Tournament history vs. double-digit seeds has been well documented, but there's another stat that stands out, too. After losing to Houston 62-60 o

The No. 4 seed Purdue Boilermakers (24-11) and the No. 1 seed Houston Cougars (32-4) will meet on Friday in the NCAA Tournament Sweet 16.

SportsLine's model revealed its college basketball predictions for Houston Cougars vs. Purdue Boilermakers on Friday in the Sweet 16 of the 2025 NCAA Tournament

Purdue University's mascot, the Boilermakers, originated from a newspaper taunt in 1891 after a football victory against Wabash College. The nickname "Boilermakers" was intended to be an insult, referencing Purdue's focus on engineering and agriculture, seen as working-class professions at the time.

Watch this Sweet 16 NCAA Tournament matchup between the No. 1 Houston Cougars (32-4) and No. 4 Purdue Boilermakers (24-11) to determine which of the squads is heading to the Midwest Region bracket

SportsLine expert Micah Roberts has revealed his Purdue Boilermakers vs. Houston Cougars picks for the Sweet 16 of the 2025 NCAA Tournament on Friday

Following Friday's Sweet 16 loss to Houston, Purdue sophomore Camden Heide talked about the brotherhood in the locker room and the season-ending loss.