The main challenge the San Francisco 49ers face against the Tampa Bay Buccaneers is defending Baker Mayfield.  He’s been so sensational this season that Robert ...

The 49ers and Bucs have taken similar paths to 4-1, hit hard by major injuries, yet making the do-or-die plays late to win ...

Both the 49ers and the Buccaneers are 4-1 after playing one-score games each week heading into Sunday’s meeting in Tampa Bay.

The 49ers got updates on receivers Jauan Jennings and Ricky Pearsall as they prepare for their Week 6 matchup against the ...

George Kittle is one of the San Francisco 49ers' most indispensable players. He's also likely to retire as a lifelong member ...

The San Francisco 49ers will take on the Tampa Bay Buccaneers on Sunday, but first they had to make a few roster changes on Saturday.

Bet Buccaneers vs. 49ers at BetMGM Sportsbook, where new users get up to $1,500 in bonus bets back if their first wager doesn ...

Given the beating Mac Jones took against the Rams, the San Francisco 49ers' biggest concern Sunday might be whether Adrian ...

It doesn't take a genius to see that Fred Warner is a stalwart player for the San Francisco 49ers. His impact on the defense is second-to-none. The performances ...

The San Francisco 49ers will be without quarterback Brock Purdy and wide receiver Ricky Pearsall, who are both sidelined with injuries, for their game against the Tampa Bay Buccaneers.

The SportsLine Projection Model has revealed its San Francisco vs. Tampa Bay picks for the 2025 NFL Week 6 contest ...

Preview the San Francisco 49ers' NFL week 6 matchup with the Buccaneers, including betting odds, tips, trends, and game ...