BARCELONA, Spain—The gout drug allopurinol on top of usual care does not improve cardiovascular outcomes in patients over age 60 who do not have gout, the ALL-HEART trial confirms. The long-running ...

The 2012 American College of Rheumatology gout treatment guidelines recommend titration of urate-lowering medication doses to achieve target serum uric acid (sUA) levels of less than 6 mg/dL. Analysis ...

Please provide your email address to receive an email when new articles are posted on . Allopurinol is noninferior to febuxostat for gout when dosed appropriately as part of a treat-to-target strategy ...

Opioid Use Linked to Low Testosterone In a Canadian study, more than half of older adults with CKD initiated allopurinol at a higher-than-recommended dose. Allopurinol doses exceeding 100 mg/d may ...

Please provide your email address to receive an email when new articles are posted on . “A meta-analysis of randomized controlled trials reporting on the comparison of allopurinol or oxypurinol with ...

Allopurinol, a frequently used gout medication, does not appear to drive up the risk for dying among gout patients who also struggle with chronic kidney disease, new research shows. The finding is ...

Trial subgroup analyses support the use of either allopurinol or febuxostat in patients with stage 3 CKD and gout. A prespecified analysis of the STOP-GOUT trial revealed that allopurinol has similar ...

Allopurinol treatment is not associated with increased mortality in patients with gout and chronic kidney disease even at 5 years after starting treatment, a study has found. Around 1 in 5 patients ...

Allopurinol has been used to treat gout for more than four decades. And a new study published Online First and in an upcoming Lancet shows that the drug prolongs exercise capacity in chronic stable ...

Credit: Shutterstock. The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum ...

The current test uses only one of the genes, and it misses many patients at risk FRIDAY, Oct. 31, 2025 (HealthDay News) — A new gene test might be able to predict which gout patients will have a bad ...