Three years ago, the NFL opened its season by pitting the Detroit Lions against the Kansas City Chiefs. It was a matchup of two very different contenders: one freshly on the upswing in Detroit, which had just established itself as a potential force thanks to a late-year push under coach Dan Campbell;

The Post’s Erich Richter makes his picks for Sunday’s and Monday’s NFL Week 6 slate. Hold your nose spot of the week. It’s London, early-morning NFL where I’m looking to back an underdog after a embarrassing defeat. With everyone selling the Jets, I’ll buy. The Jets should to run the ball on at least 60 percent of their plays Sunday.

The Chiefs and Lions are set to tangle in Week 6, and our expert NFL predictions expect Jahmyr Gibbs and Xavier Worthy hitting paydirt!

The Detroit Lions (4-1) take on the Kansas City Chiefs (2-3) on Sunday night for the first time since 2023. The Lions are two-point underdogs ahead of the game at Arrowhead Stadium, but Patrick Mahomes and the Chiefs are limping into the rematch after losing to the Jacksonville Jaguars (4-1) on Monday night.