Star QB Josh Allen and the Buffalo Bills (4-0) play the New England Patriots (2-2) on Sunday at 8:20 p.m. ET at Highmark Stadium.

The New England Patriots have beaten the Buffalo Bills 23-20 on the road, knocking off the final remaining undefeated team in the NFL this season.

Buffalo is a 7.5-point favorite in the latest Patriots vs. Bills odds from SportsLine consensus, while the over/under for total points scored is 49.5, making it the highest of Week 5.

Fresh off a blowout victory over the Panthers last week, Mike Vrabel, Drake Maye, and the Patriots will look to deliver an upset victory on Sunday night.  For Week 5, the Patriots will take on Josh Allen and the Buffalo Bills in a primetime matchup at Highmark Stadium — with kickoff set for 8:20 p.