Our cells rely on tightly regulated signaling pathways to control when they grow, divide and survive. When these regulatory ...
Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells ...
University of Virginia School of Medicine scientists have revealed how mistakes in the final step of cell division can have dire consequences for developing brain cells. The findings offer important ...
Cancer cells are distinguished from normal cells by their rapid rate of division. This high division rate can be explained by various factors, including unregulated cell cycle progression, which ...
A cell copies all of its DNA, gears up to split in two, and then just… doesn’t. It sits there, swollen with a double genome, and nobody notices. This kind of silent failure has been observed in labs ...
Resistance to cell death is a hallmark of cancer, driving tumour progression and limiting therapeutic efficacy. Metabolic cell death pathways have been identified as unique vulnerabilities in cancer, ...
Researchers discovered that a long-misunderstood protein plays a key role in helping chromosomes latch onto the right “tracks” during cell division. Instead of acting like a motor, it works more like ...
Researchers have revealed a surprising new role for a key protein in cell division. The discovery, reported in two back-to-back papers, challenges long-standing models and textbook accounts in biology ...
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