Evasion of cell death is a hallmark of cancer cells that enables them to overcome endogenous barriers to cancer development and to resist treatment. Insights into the many facets of cell death, ...
Cell migration is a key cellular process that drives major developmental programs. To mimic and mechanistically understand cell migration in these different contexts, different assays have been ...
Melanoma, a highly aggressive skin cancer with limited therapeutic options, demonstrates poor prognosis in advanced stages. Tripartite motif-containing 22 (TRIM22 ...
Human lung fibroblasts stimulated with TGF-β1 to detect extracellular collagen I (pink), alpha-smooth muscle actin (α-SMA) (green), and cell nuclei (blue) as a measure of matrix production and ...
A high-throughput cytometry workflow consolidates marker expression, proliferation, and cytokine release into a single assay ...
Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...
Esophageal squamous cell carcinoma (ESCC) is a severe health threat, being a predominant subtype of esophageal cancer and contributing significantly to cancer-related mortality globally. Despite ...