The New England Journal of Medicine

The Nucleoprotein Complement-Fixation Test in the Diagnosis of Systemic Lupus Erythematosus

A gamma-globulin factor in the serum of patients with systemic lupus erythematosus that reacts with isolated cell nuclei 1 or nucleoprotein 2,3 has been detected in many ways. 4 The standard method of ...
The New England Journal of Medicine

Attempted Cultivation of Spirochaeta Myelophthora and a Test of the Validity of the Complement-Fixation Test in Multiple Sclerosis

MULTIPLE sclerosis was recognized as a clinical entity early in the nineteenth century by Charcot. Since then its pathology and clinical symptomatology have been defined, but the etiology of this ...
Nature

Foot and Mouth Disease Virus RNA as an Antigenic Factor in the Complement-fixation Reaction Applied to the Examination of Human Tumours

Serra, Guarini et al. 1 suggested in 1958 a peculiar complement-fixation test as a very selective serological technique for identifying the blood sera of carriers of malignant tumours. You have full ...
Nature

A Purified Complement-fixing Antigen from Mycobacterium johnei

THE antigen most commonly used in complement fixation tests for Johne's disease is a suspension of the specific organism, Mycobacterium johnei. This form of antigen is not entirely satisfactory for ...