Ovarian folliculogenesis encompasses the maturation of primordial follicles through primary, secondary and antral stages to a pre-ovulatory state, followed by ovulation or atresia. This highly ...

Granulosa cells are the principal somatic component of the ovarian follicle, orchestrating oocyte maturation, steroidogenesis and follicle fate from the primordial stage through to ovulation. During ...

For the first time, researchers have shown how Mullerian inhibiting substance (MIS), also known as anti-Mullerian hormone, a key reproductive hormone, suppresses follicle development and prevents ...

A recent study published in Nature Communications by researchers at Karolinska Institutet offers new insights into the development of ovarian follicles, which are vital for female fertility as they ...

Women with obesity, even those with regular menstrual cycles, have suppressed ovarian follicle development and reduced production of reproductive hormones, which may underlie reduced fertility, ...