Langerhans cells (LCs) are a type of dendritic cell that characteristically express S100, CD1a, and langerin (CD207) and contain ultrastructural Birbeck granules. LC histiocytosis is a neoplastic ...

Langerhans cell histiocytosis (LCH) is a rare condition characterized by abnormal growth of the Langerhans cells. The proliferation of these cells leads to the formation of tumors called granulomas, ...

In an international study led by MSK, researchers reported finding key mutations driving the disease histiocytosis for nearly all of the people included. Histiocytoses are a group of blood diseases ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...