This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

This is a preview. Log in through your library . Abstract We have monitored histone acetylation during conjugation of the ciliated protozoan Tetrahymena thermophila using antibodies against the ...

Researchers from Osaka University find that neuronal activity induces gene expression at the preprepared histone acetylation sites in the nucleus by influencing transcription factors and chromatin ...

A recent study unveils new insights into the complex regulatory mechanisms behind strawberry fruit ripening. By analyzing histone modifications, researchers have mapped a detailed chromatin structure ...

Trimodality therapy for stage II-III carcinoma of the esophagus: A dose-ranging study of concurrent capecitabine, docetaxel, and thoracic radiotherapy. Sensitization of hepatocellular carcinoma (HCC) ...

Preclinical data indicate that as well as promoting histone acetylation, these agents can also affect the activity of the molecular chaperone Hsp90 resulting in increased expression of Hsp70 and ...

What is the histone code? Different chemical marks, such as acetylation, methylation, or phosphorylation, are made to numerous residues on the N-terminal tails of histone proteins. Some posit that ...

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein response (UPRmt) serves as an important retrograde regulatory pathway that ...

Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...