Suggested Citation: "5 In Vitro Alternatives to Animal Models." National Academies of Sciences, Engineering, and Medicine. 2018. Advancing Disease Modeling in Animal-Based Research in Support of ...

The integrated organ-on-chip platform offers 10–100x cost efficiency and 80% reduction in animal use, bridging the gap between preclinical NHP research and human clinical success. SUZHOU, China, SAN ...

For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...

Cerebrovascular diseases such as atherosclerosis and stroke remain a major cause of morbidity and mortality worldwide. A common feature of these diseases is vascular stenosis, i.e., the narrowing of ...

Cloud-Clone delivers a comprehensive portfolio of source-quality-controlled primary cells covering four key knee-joint cell populations. These physiologically-relevant cellular resources help ...

How controlled in vitro systems accelerate drug discovery, clarify complex disease mechanisms, and reduce reliance on animal testing.