A new method developed by researchers at KAIST and Chungnam National University could drastically streamline drug interaction testing—replacing dozens of traditional experiments with just one. The ...
In this work, by evaluating the binding and inhibitory mechanisms of such EXosite and ACTive site (EXACT) inhibitors, we show that the exosite-binding aptamer can be utilized to modulate the apparent ...
A key player in energy metabolism is phosphofructokinase-1 (PFK1) whose activity and behavior strongly influence glycolysis and thus have implications in many areas. In this research, PFK1 assays were ...
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