In eukaryotes, translation initiation is the most highly regulated phase of the translation cycle 1. Its goal is to assemble the large (60S) and small (40S) ribosomal subunits into an ...
Plasmids containing a mouse cDNA sequence encoding the enzyme dihydrofolate reductase (DHFR; tetrahydrofolate dehydrogenase; 5,6,7,8-tetrahydrofolate:NADP + oxidoreductase, EC 1.5.1.3) have been used ...
Translation is the process that makes a protein based on messenger RNA Researchers now have a 3D structure for the complex that scans mRNA to start making protein Understanding how translation begins ...
This is a preview. Log in through your library . Abstract We have determined the sequence of a ribosome-protected region of T4 rIIB mRNA labeled in vivo. The rIIB mutant HD263, which is temperature ...
Researchers have solved the the structure of the complex formed when mRNA is being scanned to find the starting point for translating RNA into a protein. The discovery provides a new understanding of ...
Genes must be expressed in precise levels and at the exact moment if the complex balance regulating cell activity is to be maintained. Messenger RNA (mRNA) conveys genetic information from DNA to ...
The regulation of mRNA transcription plays a key role in relaying signals from the environment and during development into the gene expression program of a cell. During transcription initiation, a ...
This is the first in a series describing the role of the beginning and end of the SARS-CoV-2 genome in the virus life cycle. I summarize what we know and point out what we need to know about these ...
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