The Bills have reigned over the AFC East for five straight seasons and are off to an excellent start towards a sixth in 2025. Both teams are coming off double-digit victories in Week 4, and the Patriots hope the momentum from their 42-13 beatdown of the Carolina Panthers will carry into tonight's divisional clash.

As good as Darnold was, Tampa Bay quarterback Baker Mayfield was even better, going 29-for-33 for 379 yards and two touchdowns. His 11-yard touchdown pass to Sterling Shephard with 1:08 to play tied the score at 35 and set the stage for the win.

With Tyreek Hill out for the season, Jaylen Waddle takes over as WR1. Malik Washington is expected to step up as WR2, with sixth-year veteran Nick Westbrook-Ikhine or fifth-year wideout Dee Eskridge as the WR3.

Dak Prescott found George Pickens deep for a 43-yard TD, extending the Dallas Cowboys massive lead over the New York Jets.

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Baker Mayfield and the Tampa Bay Buccaneers went to Seattle and beat the Seahawks with a last second field goal to improve to 4-1 on the season.

The Buffalo Bills certainly didn’t look like the last undefeated in team in the NFL as they played the New England Patriots on Sunday night. Penalty after penalty, missed tackle after missed tackle and mix of dropped balls and receivers failing to get open resulted in Buffalo’s first loss of the season to their AFC East foe.

Watch all of the highlights from the Detroit Lions' 37-24 Week 5 victory over the Cincinnati Bengals. Watch the best plays from the Detroit Lions in their matchup against the Cincinnati Bengals in Week 5 of the 2025 NFL season.

The Minnesota Vikings will face the Cleveland Browns in Week 5 of the NFL season on Sunday in England at Tottenham Hotspur Stadium.