Week 6 in the NFL is upon us, and it’s a perfect time for some best bets for Sunday’s action as the SI Betting team aims to roll some positive momentum into thi

Taylor Decker will miss his second straight game because of a shoulder injury, and the Detroit Lions will be without their top backup offensive tackle, too. The Lions downgraded, Decker, Gio Manu and cornerback Avonte Maddox to out for Sunday's showdown with the Kansas City Chiefs.

The Detroit Lions will be slightly shorthanded against the Kansas City Chiefs in Week 6. With cornerback Terrion Arnold already ruled out, the team added left tackle Taylor Decker, nickelback Avonte Maddox and backup offensive lineman Giovanni Manu to its weekly inactive list.

On a banner night for the Chiefs, celebrating their Super Bowl LVII victory over the Philadelphia Eagles the previous season, they owned a six-point lead early in the fourth quarter. After the Lions took a 21-20 lead, the Chiefs had two possessions. Surely, Patrick Mahomes would pull out another comeback victory.

Campbell believes the Lions still have so much room for growth, and MLive's Dungeon of Doom podcast agrees with that thinking after their 37-24 win in Cincinnati.

The Chiefs' defense had a weakness exposed in the opener against the Chargers. It happens to be what the Lions do best.

The Chiefs and Lions are set to tangle in Week 6, and our expert NFL predictions expect Jahmyr Gibbs and Xavier Worthy hitting paydirt!

The Lions covet players who can line up as both a 5-tech and a Wide-9 DE. That's exactly how Northwestern deploys Saka, even though he's undersized to play inside at around 268 pounds. He's thickly built and doesn't lack strength or anchor, however.

The Detroit Lions have been besieged by injuries to their secondary. Unfortunately, D.J. Reed, Terrion Arnold and Khalil Dorsey are all out for the foreseeable future. NFL analyst Kevin Patra recently compiled a list of each NFL team's trade needs entering Week 6 of the 2025 season.

You don't like to think of the Detroit Lions as a team that shows up on the fines list a lot, but they do. At this point, it feels like the whole team has been fined at least once.

NBA legend Charles Barkley has made his prediction for the teams that will play in the Super Bowl in February.