A new research paper was published in Volume 13 of Oncoscience on February 7, 2026, titled “Reduced immunogenicity of MYC amplified, metastatic prostate cancer.” ...

Targeting the oncogenic effects of MYC could have wide application to treat cancer patients, but so far drug development has proved challenging. Bradner, Mitsiades and colleagues approached this ...

The MYC oncogene family plays an important role in neoplastic disease, and has been extensively studied over decades. Evidence showing the N-terminal and C-terminal regions of MYC can function as a ...

MYC amplification is associated with reduced tumor immunogenicity as assessed by the recovery of IR recombination reads from prostate cancer genomics ...

Novel Treatment Targets in Sarcoma: More Than Just the GIST MYC has proven to be a highly potent oncoprotein when it is overexpressed, but is also a pleiotropic transcription factor essential for ...

Myc is one of the most frequently mutated, widely studied, and overexpressed genes implicated in cancer. Most mutations in the myc gene lead to its constitutive expression. The myc gene codes for the ...

Mice with one rather than the normal two copies of the gene Myc (also found in humans) lived 15 percent longer and had considerably healthier lives than normal mice, according to a new Brown ...

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. The poor prognosis is due in part both to late detection and the cancer’s capacity to adapt and ...

Researchers sought to determine whether the combination therapy DA-EPOCH-R would lead to responses in patients with dual MYC and BCL2-altered DLBCL.

Sperm – in theory, you only need one good one to get the job done. Nevertheless, the average pair of human testicles is estimated to crank out about a trillion of these little cells over a lifetime, ...

When cancer-driving proteins resist various treatments, Northwestern University scientists have uncovered a new solution. Don't fight them - throw them in the cellular trash. In a new study, ...