The regulation of neuronal excitability and the maintenance of an appropriate balance between excitation and inhibition are central to brain function. Inhibitory synaptic transmission, predominantly ...
Researchers identify the Munc13-1 protein as a crucial molecular pathway for working memory, linking calcium signaling to synaptic strengthening.
Working memory is a cognitive function that is essential for carrying out everyday activities and temporarily retaining ...
Schematic representation of axonal transport vesicles (blue) carrying presynaptic proteins (SV and AZ proteins). Kinesin motor proteins (KIF1A) attach these vesicles and carry them along the axons to ...
A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...
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Shared synaptic mechanism for Alzheimer's and Parkinson's disease unlocks new treatment possibilities
Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...
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