The Titans, who were 7.5-point underdogs to the Cardinals, pulled the second-largest upset of the season points spread-wise (tied with Cleveland, Week 3 vs. Green Bay). Tennessee was as long as a 30-1 underdog to win during the game at ESPN BET. The New York Jets aren't favored often, but they were Sunday.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 39-20 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Cam Ward throws for a career-high 265 yards, leading the Tennessee Titans to a 22-21 victory over the Arizona Cardinals.

Despite trailing 21-6 heading into the fourth quarter, the Titans improbably came back and beat the Arizona Cardinals 22-21 on Sunday, earning the rookie quarterback his first NFL win. If you would like a play that sums up just how weird and improbable this game was, here you go:

Houston has won two in a row to move to 2-3 and the Ravens fell to 1-4. The Texans scored on their first eight possessions, getting five touchdowns and three field goals. They had

The third-year running back raced through Tennessee’s defense and had a clear path to the end zone before letting up around the 5-yard line as Titans cornerback L’Jarius Sneed closed in fast. Demercado flipped the ball away just as Sneed reached for it, and the officials initially ruled it a touchdown.