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Prospective monitoring for immunotherapy by liquid biopsy and signal pathway alterations in head and neck cancers.

Safety and efficacy of AIC100 chimeric antigen receptor (CAR) T-cell therapy in patients with advanced thyroid cancers: Results from the phase 1 study. This is an ASCO Meeting Abstract from the 2024 ...
ascopubs.org

Alteration of p53 Pathway in Squamous Cell Carcinoma of the Head and Neck: Impact on Treatment Outcome in Patients Treated With Larynx Preservation Intent

PURPOSE: To identify the role of p53 pathway alteration(s) as predictors of treatment outcome in patients with advanced, resectable, squamous cell carcinoma (SCC) of the larynx and pharynx treated ...
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Somatic 9p24.1 alterations in HPV⁻ head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity

Somatic copy number alterations (SCNAs), generally (1) losses containing interferons and interferon-pathway genes, many on chromosome 9p, predict immune-cold, immune checkpoint therapy (ICT)-resistant ...