This image, produced by a fluorescence microscope, shows a normal renal proximal tubule, the specific nephron segment in the kidney that is impaired in the rare disease infantile cystinosis. The red, ...

In videos created by the Hughes Lab to visualize the process, adjacent nephrons form one after the other, as if they were following a beat. “It’s still a hypothesis,” adds Hughes, “but we think that ...

Each human kidney is made up of about a million filtering units called nephrons. I aim to reveal the mechanisms behind a key stage of nephron development during which a structure known as an S-shaped ...

The more tightly packed the tubules, which increases over time, the stiffer the tissue. As tubule branching continues, they found that each additional branch caused a pulse of mechanical stress, which ...

Bioprinting has been all over the news in the past several years with headline-worthy breakthroughs like printed human skin, synthetic bones, and even a fully functional mouse thyroid glan d. 3D ...

The kidneys are organs of the urinary system - which remove excess water, mineral ions and urea. Blood is transported to the kidney through the renal artery. The blood is filtered at a high pressure ...

BUFFALO, N.Y. – University at Buffalo research has identified how a misstep in the genesis of a key component of the kidney causes infantile cystinosis, a rare disease that significantly shortens the ...