The New England Patriots will be back in prime time Sunday night when they pay a visit to Highmark Stadium for an AFC East showdown with the Buffalo Bills.

New England opens with a bootleg pass to Stefon Diggs (who else?), who promptly finds open grass for a first down. But then the Bills defense counters immediately, swallowing up Rhamondre Stevenson's first carry and then sacking Maye on third-and-long. Already we can see this matchup will be a test for the Patriots' offensive front.

The Buffalo Bills suffered their first loss of the season Sunday night, falling 23-20 to their division rival New England Patriots. The Bills had 11 penalties and three turnovers, which proved costly in the defeat.

Here are the full lists of game day inactives for both the Bills and Patriots ahead of their Week 5 'Sunday Night Football' game.

In Week 5 on "Sunday Night Football," the Bills (4-1) lost 23-20 against the Patriots (3-2) at Highmark Stadium. Buffalo was done in by a couple of mistakes on their own end without a doubt. While the Bills battled to make it close, the Pats were too much, including a huge game from former Bill Stefon Diggs.

Milton Williams of the New England Patriots missed practice, and that's a bad sign for the showdown against the Bills.

The final two unbeaten records in the NFL failed to make it beyond week five as the Philadelphia Eagles and Buffalo Bills suffered shock home defeats. The Denver Broncos went from dark horses to headline-makers thanks to a superb comeback win against Super Bowl champions the Eagles,

The New England Patriots will have defensive tackle Milton Williams for Sunday night's prime time showdown with the Buffalo Bills.