A newly developed mouse model enables real-time visualization of RNA Polymerase II (RNAP2) during DNA transcription, as ...

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 3 (January 18, 2022), pp. 1-7 (7 pages) Elongating RNA polymerase II (Pol II) can be paused or arrested ...

Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries the information contained within DNA to the ribosomes, where the genetic information is synthesized into ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 5 (Feb. 27, 2001), pp. 2550-2554 (5 pages) The yeast transcriptional repressor Tup1, tethered to DNA, ...

New research by German scientists has uncovered another form of coronavirus polymerase. The current polymerase thought to be used for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this underappreciated protein ensures the rhythmic expression of genes in skeletal muscle, ...

Researchers have identified a library of molecules that shut down the SARS-CoV-2 polymerase reaction, a key step that establishes the potential of these molecules as lead compounds to be further ...

Invented 30 years ago, polymerase chain reaction , or PCR, is one of the greatest inventions of the 20th century. It’s the technique that allows researchers to map genomes, find genetic causes of ...