A team of researchers has developed an innovative method to design complicated all-α proteins, characterized by their non-uniformly arranged α-helices as seen in hemoglobin. Employing their novel ...

Researchers have constructed a protein out of amino acids not found in natural proteins, discovering that they can form a complex, stable structure closely resembling a natural protein. Their findings ...

In a recent study published in the International Journal of Molecular Sciences, researchers characterized truncated forms of LCB1, a de novo-designed mini-protein, against severe acute respiratory ...

The amino acid sequence rules that specify β-sheet structure in proteins remain obscure. A subclass of β-sheet proteins, parallel β-helices, represent a processive folding of the chain into an ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

(Nanowerk News) Nature is filled with extraordinarily precise molecular shapes that fit together like a hand in glove. Proteins, for example, can assemble into a wide variety of well-defined shapes ...

Chemists discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Knowledge of this structure may make it possible to design drugs that could block transport ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring ...