The 2025 NFL season has intensified with Week 5 bringing a thrilling Sunday lineup on October 5. With bye weeks sidelining the Falcons, Bears, Packers, and Steelers. Undefeated teams like the Philadelphia Eagles and Buffalo Bills face tough challenges, while a London matchup and rookie debuts add excitement.

Content on this page may include affiliate links. If you click and sign up/place a wager, we may receive compensation at no cost to you. The Week 5 NFL schedule includes 12 games on Sunday, including a rapid-fire six-game window at 1 p.

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