The Buffalo Bills face the Houston Texans on Thursday, Nov. 20, 2025 (11/20/25) at NRG Stadium in Houston, Texas.

The Texans mounted an impressive comeback against the Jacksonville Jaguars in Week 10 and found a way to win in Tennessee last Sunday despite not scoring a single point in the first half, but the Bills are a different kind of test. Buffalo covers the spread in prime time. Pick: Bills -5.5; Under 43.5

All the ways you can watch, stream, and tune-in to Week 13 between the Texans and the Indianapolis Colts at Lucas Oil Stadium on November 30.

The Buffalo Bills and Houston Texans take the field for NFL Thursday Night Football tonight in Week 12. TNF start time, TV schedule and how to watch.

MVP quarterback Josh Allen and the Buffalo Bills visit the short-handed Houston Texans led by Nico Collins and fill-in QB Davis Mills tonight in a Thursday Night Football showdown tonight.

Big Sarge LIVE from Nissan Stadium dissects the Texans' gritty win, revealing crucial plays and playoff-altering takeaways before their brutal upcoming schedule.

USA Today's NFL experts make their picks for a Week 13 showdown between the Dallas Cowboys and Kansas City Chiefs