Quarterback injuries throw everything for a loop in the NFL, and that's certainly been the case in the early stages of 2025. That remains the case for Week 6, but signal-callers aren't the only big injuries worth monitoring this weekend.

Jayden Daniels was effective but not spectacular last week against a stiff Chargers pass defense (231 yards, 1 TD).

We’ve made it to another Thursday, which means it is officially time to kick off Week 6 of the 2025-26 NFL regular season with a primetime showdown in the NFC East. On Thursday Night Football, the New York Giants host the defending Super Bowl champion Philadelphia Eagles at MetLife Stadium.

For the fourth straight Thursday and the fifth time in five weeks, the NFL schedule begins with a divisional clash. The reigning Super Bowl champion Philadelphia Eagles are at MetLife Stadium to battle the rival Giants looking to bounce back after their first loss of 2025.