Soon after the completion of the Human Genome Project, it became clear that the approximately 20,000 DNA fragments identified as protein-coding sequences were woefully inadequate to account for the ...

An error in protein conformation can lead to disease. What are the genetic and molecular causes for incorrectly formed proteins? molecules. In 1917 the German chemist ...

Scientists at St. Jude Children's Research Hospital have created a database that provides updated predicted structures on a ...

Today’s clinicians use recombinant therapeutic proteins, such as monoclonal antibodies, to treat many diseases, from autoimmune disorders to cancer and beyond. Nonetheless, sequence variants (SVs), ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

Whether you’re interested in why a living system works as it does or the reasons it goes awry, proteins are a critical part of the molecular picture. The proteins circulating in a person’s plasma can ...