Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK Correspondence to: Dr R Al-Shahi, Bramwell Dott Building, Department of Clinical Neurosciences, ...

Objectives: To test a new neurological sign, the “abductor sign,” which can distinguish between organic and non-organic leg paresis using synergic movements of the bilateral hip abductors. Methods: ...

1 Department of Neurology, Medical Centre Haaglanden, The Hague, The Netherlands 2 Department of Neurology, Maasstad Hospital, Rotterdam, The Netherlands 3 Department of Radiology, Medical Centre ...

Objective To explore whether age at onset increased over time despite a shortened interval from the initial clinical demyelinating event to the diagnosis of multiple sclerosis (MS), as promoted by ...

Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is a hereditary cause of cerebral small-vessel disease associated with one of many ...

Objective Deep brain stimulation (DBS) reduces depressive symptoms in approximately 40%–60% of patients with treatment-resistant depression (TRD), but data on long-term efficacy and safety are scarce.

Background Brain imaging studies investigating grey matter in functional neurological disorder (FND) have used univariate approaches to report group-level differences compared with healthy controls ...

Objective To perform a systematic review of cases reported in the literature in which a peripheral trauma preceded the onset of a movement disorder (MD). Methods Two reviewers independently searched ...

2 Department of Neurology, Kosei Chuo General Hospital, Tokyo, Japan 3 Department of Neurology, National Hospital Organization Yokohama Medical Center, Yokohama, Kanagawa, Japan 4 Department of ...

Introduction Sarcoidosis is a granulomatous disease with protean manifestations. The aetiology is not fully understood. Infectious agents are considered to potentially contribute to its pathogenesis.

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Saccades, including fast phases of nystagmus, disappear during drowsiness and non-rapid eye movement (NREM) sleep, but are present during the alert state and REM sleep. The purpose of this study was ...