How does APOE4 aggravate the risk of Alzheimer’s disease, and how does APOE2 protect against it? Some scientists are turning to the plasma proteome for clues. In the May 15 Nature Aging, a group led ...

Billions of years have passed since mitochondria left their freewheeling proteobacterial days behind them, but the nucleic acids within these endosymbiotic organelles still retain features of their ...

Kenneth Chen, M.D., Ph.D. Stanford University School of Medicine Contact Information Kenneth Chen, M.D., Ph.D. United States ...

Professional Information Matthew Flinders Fellow; Associate Professor in NeuroscienceFlinders University https://researchers.mq.edu.au/en/persons/arne-ittner ...

“I’m looking for a cheetah.” The curious statement popped onto the computer screen of a man with amyotrophic lateral sclerosis who could no longer speak or move below the neck. It was his second time ...

Does the Alzheimer’s brain contain too much sugar? Perhaps so, according to a group led by Ramon Sun at the University of Florida, Gainesville. As reported in the June 9 Nature Metabolism, the ...

Researchers propose unifying TDP-43 proteinopathies under one umbrella. TDP-43-associated neurodegenerative disease (TAND) would include ALS, FTD, and LATE. A machine learning algorithm, MARBLE, ...

Proteomic panels come up short in the search for a plasma biomarker of Lewy bodies. AI may help.

Contact Information Faisal Naqvi Ireland Professional Information ...

Joseph A. Vita, MD Professor Boston University https://www.bumc.bu.edu/camed/profile/naomi-hamburg/ ...

This database is a repository of normal genetic variability, designed to be a tool for researchers who study neurodegenerative disease. It contains whole-exome sequencing results from nearly 500 ...

Score another one for amyloid immunotherapy. The anti-pyroglutamated amyloid antibody donanemab has posted positive top-line results in the Phase 3 Trailblazer-Alz2 study, according to an Eli Lilly ...