San Francisco 49ers vs Arizona Cardinals picks, predictions, odds, win probabilities for NFL Week 3 Sunday game on Sept. 21, 2025. Who will win today?

What's the Arizona Cardinals vs San Francisco 49ers score? Follow our live score updates for latest news, highlights, analysis from NFL Week 3 game.

SANTA CLARA, Calif. — Through two weeks, the Arizona Cardinals were 2-0 — with a caveat. Both wins came against NFC bottom-dwellers. Both had underwhelming elements, with comfortable leads nearly ...

Even without Brock Purdy, the San Francisco 49ers were able to get it done. Quarterback Mac Jones led the way as the 49ers edged the Arizona Cardinals 16-15 on Sunday at Levi’s Stadium, thanks to Eddy ...

After starting the season 2-0 on the road, the San Francisco 49ers returned home for a Week 3 NFC West battle with the Arizona Cardinals at Levi's Stadium on Sunday, and Kyle Shanahan's team earned a ...

SANTA CLARA -- The 49ers just beat the Arizona Cardinals 16-15 on a last-second field goal to improve their record to 3-0. Here are the 49ers' grades for this performance. Mac Jones wasn't great. His ...

Look back on our live updates of the game, which was played at the 49ers' Levi's Stadium in Santa Clara, California. San Francisco's Eddy Pineiro kicked a 35-yard field goal as time expired to beat ...