The Detroit Lions go on the road to face the Kansas City Chiefs in a Week 6 NFL matchup on Sunday Night Football.

SNF Week 6 features a clash between the Chiefs and Lions in Kansas City. Check out the best NFL DFS lineups for this clash of ...

Despite the loss last week, the Chiefs racked up 476 yards of offense and an impressive 7.6 yards per play. The week prior, ...

Three years ago, the NFL opened its season by pitting the Detroit Lions against the Kansas City Chiefs. It was a matchup of ...

SportsLine's Data Science team, AI Predictions and AI Ratings have found top NFL longshot picks, player props for NFL Week 6 ...

Week 6 in the NFL is upon us, and it’s a perfect time for some best bets for Sunday’s action as the SI Betting team aims to ...

The Chiefs and Lions are set to tangle in Week 6, and our expert NFL predictions expect Jahmyr Gibbs and Xavier Worthy ...

Though the game will be played at a neutral site, Tottenham Hotspur Stadium, this will be a Jets home game, and not just ...

The Jags lead the league in turnover differential at plus-8, and have an NFL-best 10 interceptions to go with four fumbles recovered. Crucially, they have scored six touchdowns and two field goals off ...

Week 6 in the 2025 NFL season features some fantastic matchups on Sunday, culminating with a marquee matchup between the Detroit Lions and Kansas City Chiefs on ...

Preview the Week 6 matchup between the Kansas City Chiefs and Detroit Lions with predictions, odds, over/under, spread, betting lines and more.

NFL Week 6 is here and we asked USA TODAY Sports' staff for their top bets for the entire NFL slate. Here are their picks and predictions.