New experimental research suggests statin-related muscle symptoms may be linked to inflammatory signalling and disrupted muscle metabolism. The study points to reduced isoprenoid production, impaired ...

According to researchers, more than 98% of people who are eligible to take statins face a very low risk of developing serious ...

An experimental study in Science Advances shows that statins, primarily fluvastatin in these experiments, may promote ...

A new study overturns long-held assumptions about the cause of the rare inflammatory disorder MKD, identifying a previously ...

The new pathway aligns with health leaders' stated goal of reducing red tape for cell and gene therapies, but contrasts with the surprising recent rejections of ...

Jason is a general assignment reporter, with particular focus on genetic medicine and rare disease. Confidential tips can be sent on Signal at JasonMast.77. Lizzy leads STAT’s coverage of the FDA. Her ...

Experimental models and clinical evidence suggest that the gut and the central nervous system (CNS) interact in a multifactorial, bidirectional manner. A third player, the immune system, has recently ...

Health officials including FDA Commissioner Marty Makary, M.D., have openly voiced support for the development of novel cell and gene therapies. (Brendan Smialowski/AFP via Getty Images) In a highly ...

This study presents valuable findings on the role of KLF6 in in vitro endothelial cells exposed to altered (high or low) shear stress with a customized microfluidic device to investigate mechanisms of ...

The team demonstrated for the first time that atorvastatin can directly attack liver cancer cells by blocking the " mevalonate pathway," a metabolic route crucial for cancer cell survival. This ...

Doximity recently rolled out a new artificial intelligence medical scribe that is available free of charge to all verified U.S. physicians. (GraphicDesigner ...