The New England Patriots come into the game sitting at 3-2 and are arguably coming off their biggest win in years.

The Tampa Bay Buccaneers (4-1) will meet the San Francisco 49ers (4-1) at Raymond James Stadium on Sunday, Oct. 12 at 4:25 p.m. ET, and our computer prediction is a close victory by the Buccaneers, 24...

Tampa Bay is a 3.5-point favorite in the latest 49ers vs. Buccaneers odds from SportsLine consensus, while the over/under for total points scored is 46.5.