Not long after nearly losing a fumble on a sack, Mac Jones finally unravels for the 49ers, tossing a deep pick to Jamel Dean that just might seal a home victory for Tampa Bay, which is getting heroic stuff from its own gunslinger in Baker Mayfield:

Baker Mayfield pulled off two astounding highlights during the second half of the Buccaneers' matchup against the 49ers on Sunday.

Watch QB Baker Mayfield's top highlights from the Tampa Bay Buccaneers 30-19 victory over the San Francisco 49ers.

San Francisco 49ers kicker Eddy Piñeiro puts the 49ers on the board with a 52-yard field goal against Tampa Bay Buccaneers.

Los Angeles Rams tight end Davis Allen corrals a 20-yard pass from quarterback Matthew Stafford against the San Francisco 49ers at SoFi Stadium.

WR Kameron Johnson catches a 34-yard touchdown pass from QB Baker Mayfield against the San Francisco 49ers in Week 6 of the 2025 NFL season.

The Indianapolis Colts are one of eight NFL teams with just one loss. Says one national expert: 'Maybe the Colts should be ranked higher. Nothing in their profile indicates this great start has been a fluke.'

Los Angeles Rams quarterback Matthew Stafford's best throws from his three touchdown game vs. the San Francisco 49ers during Week 5 of the 2025 NFL season.

Another week and a new set of injuries for the Tampa Bay Buccaneers look to leave them shorthanded when the 4-1 San Francisco 49ers come to town on Sunday.  San