The San Francisco 49ers scored on the first official snap of the game and didn't look back, routing the Cardinals in 41-22 fashion. Arizona now drops to 3-7 on the year, and it was perhaps their most ...

The Arizona Cardinals truly beat themselves, and head coach Jonathan Gannon delivered this message to his locker room.

Amid all the chaos and uncertainty in the conference title races, one thing is certain: James Madison will play in the Sun ...

First baseman Josh Naylor and the Seattle Mariners are finalizing a five-year contract, a person with knowledge of the deal told The Associated Press on Sunday ...

With two weeks left in the season, just one team has clinched a conference title game berth, here is how the rest get in to a ...

Officials said multiple inmates at an Arizona prison were taken to a hospital after they were found seizing Sunday morning.

After a frustrating six-week wait to return from injury, 49ers quarterback Brock Purdy didn't take long to get back into a ...