The Indianapolis Colts take the AFC South lead by extending the Arizona Cardinals' losing streak: Stats, scores.

Ahead of the 2025 NFL season, very few would have predicted that the Indianapolis Colts would look like arguably the best team in the league entering Week 6 action.

Find out how to watch the NFL Week 6 game between the Indianapolis Colts and Arizona Cardinals, as well as the latest odds and updated injury report.

The Colts have played one down-to-the-wire game, which they won. The Cardinals have played three straight nail-biters, and they haven't gone well.

Jacoby Brissett, filling in for an injured Kyler Murray, finished 27-for-44 for 320 yards and two touchdowns with one interception.

Congratulations are in order for an Indianapolis Colts cheerleader who got the surprise of her life when her now-fiancé snuck onto the field to pop the question. The NFL cheerleader, named Mika, thoug

The Arizona Cardinals visit the Indianapolis Colts in NFL Week 6 action. Here are the inactive players for both teams.

Jim Irsay had three children who have assumed ownership of the Indianapolis Colts following his death in May 2025. Here is everything to know about Jim Iray’s daughters: Carlie, Casey and Kalen.

Indianapolis Colts head coach Shane Steichen will decide if Riley Leonard or Brett Rypien backs up Daniel Jones.