Throughout the course of multiple sclerosis, gradually progressive neurologic impairment can occur, which has been called ...

Tolebrutinib is an oral, brain-penetrant, and bioactive Bruton’s tyrosine kinase inhibitor that modulates peripheral ...

The National Academy of Medicine convened a workshop of experts and published a report that reviews the progress generative AI has achieved in health care and discusses future opportunities and ...

The incidence of prostate cancer is increasing. Screening with an assay of prostate-specific antigen (PSA) has a high rate for false positive results. Genomewide association studies have ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Autoimmune generalized myasthenia gravis is a disease that manifests with fluctuating muscle weakness. Inebilizumab is a monoclonal antibody that depletes CD19+ B cells, which are central to ...

Recognizing that financially strapped students find their residency choices constrained by cost-of-living considerations, Mass General Brigham began supplementing the salaries of residents in need.

During the American Revolution, more than in any subsequent U.S. war, doctors played critical roles beyond their medical functions. A key leader at the outset of the war was Dr. Joseph Warren.

The case description for a Case Records of the Massachusetts General Hospital appears below. A 56-year-old woman experiencing homelessness was evaluated at this hospital because of sore throat and ...