The Dallas Cowboys have reportedly placed star running back Miles Sanders on the season-ending injured reserve.

To open the week, the Cowboys have some of their starting offensive lineman back on the field. Tyler Smith (knee) and Tyler Guyton (concussion) were back at practice in a limited capacity. CeeDee Lamb (ankle) did not practice, but he was seen working on the side of practice with the training staff, as was Tyler Booker (knee).

Trevon Diggs has been dealing with a knee injury throughout the 2025 NFL season. He was limited in practice all week for the Dallas Cowboys. While he was listed as questionable heading into Sunday, the Cowboys announced that Diggs would be active in Week 6.

The Cowboys will activate Jalen Cropper for the Week 6 matchup with the Panthers as the Miles Sanders injury reshapes the roster.

The Dallas Cowboys are not doing well on the injury front at the moment. Heading into their Week 5 matchup with the New York Jets, they are truly suffering on the offensive side of the ball. Not only did they leave their game against the Green Bay Packers without a notch in the win column,

The Dallas Cowboys' injury report for Week 6 may be a long one, but the team got some good news for one of their starting offensive lineman.

Dak Prescott and the Dallas Cowboys played arguably their best game of the 2025 NFL season under first-year head coach Brian Schottenheimer, taking down Justin Fields and the New York Jets 37-22 in Week 5. Now, the Cowboys will look for a second straight win in Week 6, facing Bryce Young and the Carolina Panthers in Charlotte.