The Week 6 NFL schedule has a bit of everything with the biggest NFL spread of the season, a potential Super Bowl preview on ...

Week 6 has plenty of intriguing matchups on deck, and already is off the heels of the New York Giants upsetting the ...

He’s the first NFL rookie with at least 25 receptions and 400 receiving yards, plus five touchdowns, in his first five games.

The 49ers (4-1) travel across the country to face the Bucs (4-1), and both teams are coming off entertaining 3-point wins on ...

With a 1 1/2-game lead in the AFC North, SportsLine's AI is expecting a big Steelers win and rates their cover as a B pick ...

The Colts have played one down-to-the-wire game, which they won. The Cardinals have played three straight nail-biters, and ...

The Miami Dolphins play the Los Angeles Chargers in Week 6 of the 2025 NFL season. Who wins? See our predictions and picks, ...

The Week 6 NFL slate is headlined by a fascinating Sunday night matchup between the Lions and a Chiefs team looking to avoid ...

It's already Week 6 of the 2025 NFL season. Here's a look at expert predictions, picks against the spread and odds for every ...

The line is moving toward the Chiefs, likely because the Lions secondary is in shambles. Cornerbacks Terrion Arnold and D.J.

Our Week 6 ATS picks start with the NFC East clash between the Eagles and Giants on Thursday Night Football and include ...

Sam Farmer makes his picks and predictions for Week 6 of the NFL season, with the Lions defeating the Chiefs in prime time ...