Objective Glomerular immune complex deposition plays a central role in lupus nephritis (LN), but the prognostic relevance of individual immunoglobulin components remains unclear. This study aimed to ...
Background Systemic lupus erythematosus (SLE) often mimics the symptoms of other diseases, and the interval between symptom onset and diagnosis remains long in these patients. The aim of this study is ...
Objective No studies have investigated the incidence and correlation of scarring and dyspigmentation across all cutaneous ...
22 Historical aspects of B-cell depletion in SLE (8 October, 2025) ...
*This non-accredited industry-sponsored symposium is not part of the accredited CME programme.
Belimumab (BEL) is a monoclonal antibody that selectively binds to BLyS, a survival factor for B cells, while anifrolumab (ANI) is a monoclonal antibody that binds to the type I interferon (IFN) ...
Fumaric acid esters in cutaneous lupus erythematosus Fumaric acid esters (FAEs), established immunomodulatory agents in the treatment of psoriasis and multiple sclerosis, have been investigated for ...
In 1998 Edwards and Cambridge from University College London became increasingly convinced that B-lymphocytes were critically involved in the development of rheumatoid arthritis. 1 For some people at ...
Lupus nephritis is a serious complication of systemic lupus erythematosus and a major driver of morbidity and mortality. Current clinical monitoring relies heavily on proteinuria and kidney ...
Low disease activity and remission are recognized as important goals in the treatment of patients with lupus and as valuable outcomes in epidemiological research and in clinical trials. The former is ...
Cutaneous lupus erythematosus (CLE) has a large impact on quality of life (QoL). The goal of remission is important, but until recently has been difficult to achieve for many patients. There is now a ...
Glucocorticoids represent the most potent class of anti-inflammatory drugs. However, their anti-inflammatory mode of action has been incompletely understood. Recent insights have revealed a key role ...
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