Tumors trigger T-cell exhaustion through a TSP-1–CD47 signaling pathway. Blocking it can restore immune strength and improve cancer treatment.
AAV-SLB101 is a rationally designed capsid developed for enhanced skeletal muscle, cardiac tropism, and reduced biodistribution to the liver.
The Fugaku supercomputer builds a highly detailed virtual mouse cortex with millions of neurons enabling unprecedented ...
Korro Bio saw its stock reach all-time lows on disappointing data for its lead pipeline candidate, while Intellia Therapeutics saw analyst downgrades on safety concerns despite releasing positive data ...
Microrobots could be precisely directed, under clinical conditions, by integrating systems for navigation, therapeutic ...
Prophylactic HPV vaccines prevent infection but not existing disease. A nasal nanogel vaccine shows preclinical promise for ...
Opinion
A Future Beyond Animal Testing: Why ORIVA Matters and How Computational Models Bridge the Gap
Animal testing is costly, slow, and poorly predictive. ORIVA offers a human-relevant alternative with the potential to change that.
Merck & Co. has agreed to acquire Cidara Therapeutics for approximately $9.2 billion, the companies said, in a deal designed to bolster the buyer’s antiviral portfolio with a Phase III drug designed ...
GATC brought together a broad coalition of researchers and executives in cell and gene therapy, gene editing, drug discovery and AI as well as patients and advocates.
Findings suggest that urinary ceramide levels could serve as an early biomarker for acute kidney injury, helping doctors identify patients at risk.
Multiomics analysis of immune rejection of a pig kidney transplanted into a human decedent uncovers key antibody and T cell responses.
There is an unmet need for improving efficacy of both disease and infection prevention of pertussis, whooping cough.
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